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Bulgaria - Final Regulatory Action
Phosphamidon (Soluble liquid formulations of the substance that exceed 1000 g active ingredient/l) CAS number:
Date circular:

Chemical name: Phosphoric acid, 2-chloro-3-(diethylamino)-1-methyl-3-oxo-1-propenyl dimethyl ester

Final regulatory action has been taken for the category: Pesticide

Final regulatory action: The chemical is Banned

Use or uses prohibited by the final regulatory action:

All formulations and uses are prohibited.

Pesticide use or uses that remain allowed:


The final regulatory action was based on a risk or hazard evaluation: No

Summary of the final regulatory action:

It is prohibited to production, use and place on the market all plant protection products containing Phosphamidon according to annual adopted list of active ingredients banned for use in plant protection products under the lant Protection Act. The chemical is designated as a PIC chemical. (Annex I of the Regulation on the import and export of certain dangerous chemicals on the Bulgarian territory). The import and use of the chemical for research or laboratory purposes in quantities less than 10 kg are allowed.

The reasons for the final regulatory action were relevant to: Human health

Summary of known hazards and risks to human health:

Acute Health Effects: Exposure to Phosphamidon can cause rapid, fatal, organophosphate poisoning with headache, dizziness, blurred vision, tightness in the chest, sweating, nausea and vomiting, diarrhea, muscle twitching, convulsions, coma and death. Breathing Phosphamidon can irritate the lungs causing coughing and/or shortness of breath. Higher exposures can cause a build-up of fluid in the lungs (pulmonary edema), a medical emergency, with severe shortness of breath.
Chronic Health Effects: Phosphamidon may cause mutations (genetic changes). Whether or not it poses a cancer hazard needs further study. There is no evidence that Phosphamidon affects reproduction.
Other Long-Term Effects: Phosphamidon may affect the liver and kidneys. High or repeated exposure may damage the nerves causing weakness, "pins and needles," and poor coordination in arms and legs.

Expected effect of the final regulatory action in relation to human health:

A reduction of hazards and risks to human health.

Summary of known hazards and risks to the environment:

Due to highly toxicity of phosphamidon to fishes, aquatic organisms and bees.

Expected effect of the final regulatory action in relation to the environment:

Total reduction of risks linked to phosphamidon to protect aquatic wildlife and plants.

Date of entry into force of the final regulatory action: 01/01/2004