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Peru - Final Regulatory Action
Endosulfan CAS number:
Date circular:

Chemical name: 6,9-Methano-2,4,3-benzodioxathiepin, 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-, 3-oxide

Final regulatory action has been taken for the category: Pesticide

Final regulatory action: The chemical is Banned

Use or uses prohibited by the final regulatory action:

All agricultural pesticides with Endosulfan active ingredient.

Pesticide use or uses that remain allowed:


The final regulatory action was based on a risk or hazard evaluation: Yes

Summary of the final regulatory action:

Cancels registration and prohibits register of new agricultural chemical pesticides with Endosulfan, Aldicarb and Lead Arsenate active ingredient.

The reasons for the final regulatory action were relevant to: Environment

Summary of known hazards and risks to the environment:

Considering the information on the environmental fate of endosulfan active ingredient, it is indicated that this substance is poorly soluble in water, is transported over long distances, bioaccumulates, volatile, no potential for leaching to groundwaters, persistent in soil and water, undergoes to hydrolysis and photolysis. The main degradation routes are the microbial (oxidation), hydrolysis and photolysis. The main degradation metabolites in the environment are: Endosulfan sulfate, Endosulfan dial, Endosulfan lactone, Endosulfan ether, Endosulfan hydroxy-ether, Endosulfan carboxylic acid. Endosulfan sulfate is the major degradation product, it has the same toxicity of the parent compound but it is even more persistent. In many cases we use the term "Endosulfan sum" or " Endosulfan" including the two isomers, alpha and beta, and the major degradation product, Endosulfan sulfate. According to the assessment of ecotoxicological data, Endosulfan is classified as highly toxic to birds, slightly toxic to bees, very toxic to earthworms, extremely toxic to aquatic organisms vertebrates and invertebrates, and highly toxic to algae, therefore meets with the criteria for inclusion in the list of Persistent Organic Pollutants (POPs) and in Annex III of the Rotterdam Convention. Also note that Endosulfan is not included, to date, in the list of restricted or prohibited substances by SENASA in Peru, ( The Ministry of Environment (MINAM) and the Technical Group for Substances (GTSQ) called for a ban in the country. The manufacturer and registrant of Endosulfan a.i. in Peru, BAYER SA, decided to withdraw all registered pesticides with Endosulfan a.i. from the national market.

Expected effect of the final regulatory action in relation to the environment:

Cancelation of all registers of agricultural pesticides with Endosulfan active ingredient.

Date of entry into force of the final regulatory action: 01/02/2012