Chemical name: Sulfuric acid, dithallium(1+) salt

Final regulatory action has been taken for the category: Industrial

Final regulatory action: The chemical is Banned

Use or uses prohibited by the final regulatory action:

Thallium sulfate and mixtures containing 1% or more of thallium sulfate are banned for manufacture, import and use as an industrial chemical. No remaining uses are allowed, except for the use mentioned in the subsection below.

Use or uses that remain allowed:

Use of the chemical for research or laboratory purposes is allowed.

The final regulatory action was based on a risk or hazard evaluation: Yes

Summary of the final regulatory action:

Thallium sulphate and mixtures containing 1% or more of Thallium sulphate are banned for manufacture, import and use as an industrial chemical. No remaining uses are allowed.

The reasons for the final regulatory action were relevant to: Human health

Summary of known hazards and risks to human health:

Thallium sulfate has acute toxic effects on humans. Studies in rats and mice have documented reduced foetal body weights, delayed skeletal ossification and an increased incidence of foetal hydronephrosis. When rats were fed thallium sulfate for long-term exposures, increased numbers of abnormal sperm, reduced sperm motility, Sertoli cell vacuolisation and distortion in the seminiferous epithelium were observed.

Expected effect of the final regulatory action in relation to human health:

It is expected that the regulatory action will significantly reduce the potential risk of those toxic effects to workers and others dealing with the chemical.

Date of entry into force of the final regulatory action: 13/11/2003

Thallium sulfate and its mixtures were banned for manufacture use and import by MOE's Public Notice No. 1991-44(9 August 1991). The Notice was amended several times and final amended notice took into force on 13 November 2003.